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Christian benedict, PI

I have a diverse scientific background, from nutritional science to neuroscience and pharmacology. Since August 2022, I have been a tenured Associate Professor in Pharmacology at Uppsala University. I head up a team of scientists, which, thanks to financial support from the Novo Nordisk Foundation and Swedish Brain Foundation, studies the health effects of disrupted sleep. To begin with, we identified several mechanisms possibly underlying the increased risk of weight gain and impaired glycaemic control among people with chronically impaired sleep patterns. For example, in a multi-group collaborative effort, omic-based evidence revealed that sleep loss shifts skeletal muscle's oxidation from glucose to non-glucose source and favors the build-up of energy deposits in the fat tissue. Furthermore, our research has demonstrated that sleep loss poses a considerable burden on the brain and increases the risk of neurodegenerative diseases like Alzheimer's disease. In conclusion, our research has significantly contributed to our understanding of why sleep is critical for numerous aspects of health, including weight control, glucose metabolism, and brain health.

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